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These are notes were the reference from a lecture given at the Danby Society of Downing College on 14 February 2018 under the title ‘Any questions? The challenges of Science in a data driven world’ The era of the History of Science ushered by the publication of Newton’s Principia Mathematica is coming to an end; we need to take stock of this and consider the possibilities that a new, data centered and driven reality offers to us. The inflexion point that […]
van den Brink, S.C., Alemany, A., van Batenburg, V. et al. Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids. Nature (2020).
Beccari, L., Moris, N., Girgin, M. et al. Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids. Nature (2018).
The lab has strong collaborations with Nicole Gorfinkiel (Centro Biologia Molecular, Madrid, Spain), Anne Grapin-Botton (Danish stem cell center), Ana Katerina Hadjantonakis (Sloan Kettering Institute, New York, USA), Kathryn Lilley (Department of Biochemistry), Jenny Nichols (Wellcome-MRC Cambridge Stem Cell Institute), and Emma Rawlins (Gurdon Institute).
We also have strong collaborations with physicists and engineers which respond to the increasing need to trascend the data that is generated by classical biological approaches. In particular we have close interactions with Jordi Garcia Ojalvo (Universidad Pompeu Fabra) and Jeremy Gunawardena (Department of Systems Biology).